Review



anti il 1r antibody  (Bio X Cell)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    Bio X Cell anti il 1r antibody
    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for <t>IL-1R</t> Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t
    Anti Il 1r Antibody, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 50 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti il 1r antibody/product/Bio X Cell
    Average 94 stars, based on 50 article reviews
    anti il 1r antibody - by Bioz Stars, 2026-03
    94/100 stars

    Images

    1) Product Images from "The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation"

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation

    Journal: Cellular and Molecular Immunology

    doi: 10.1038/s41423-025-01264-z

    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for IL-1R Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t
    Figure Legend Snippet: Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for IL-1R Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t

    Techniques Used: Inhibition, Control, Flow Cytometry, Staining, Expressing



    Similar Products

    il 1r  (Sino Biological)
    94
    Sino Biological il 1r
    Il 1r, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il 1r/product/Sino Biological
    Average 94 stars, based on 1 article reviews
    il 1r - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    anti il 1r antibody  (Bio X Cell)
    94
    Bio X Cell anti il 1r antibody
    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for <t>IL-1R</t> Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t
    Anti Il 1r Antibody, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti il 1r antibody/product/Bio X Cell
    Average 94 stars, based on 1 article reviews
    anti il 1r antibody - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    anti-il-1r antibody be0256  (Bio X Cell)
    90
    Bio X Cell anti-il-1r antibody be0256
    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for <t>IL-1R</t> Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t
    Anti Il 1r Antibody Be0256, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti-il-1r antibody be0256/product/Bio X Cell
    Average 90 stars, based on 1 article reviews
    anti-il-1r antibody be0256 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    anti–il-1r antibody jama-147  (Bio X Cell)
    90
    Bio X Cell anti–il-1r antibody jama-147
    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for <t>IL-1R</t> Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t
    Anti–Il 1r Antibody Jama 147, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti–il-1r antibody jama-147/product/Bio X Cell
    Average 90 stars, based on 1 article reviews
    anti–il-1r antibody jama-147 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    anti il 10  (Santa Cruz Biotechnology)
    93
    Santa Cruz Biotechnology anti il 10
    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for <t>IL-1R</t> Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t
    Anti Il 10, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti il 10/product/Santa Cruz Biotechnology
    Average 93 stars, based on 1 article reviews
    anti il 10 - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    il 1r antibody  (Bio X Cell)
    94
    Bio X Cell il 1r antibody
    (A) RT-qPCR results of Ovol1 and Il1a expression in epidermal cells of the HDM/SEB-treated mice at day 7. n = 3 mice per group. (B) Experimental design for <t>IL-1R</t> Ab treatment in (C-K). Samples were harvested at day 11 after treatment for downstream analysis. IgG was used as a control. (C-D) Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (E) Representative photographs of IgG- or IL-1R Ab-treated SSKO mice. (F) Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (G) Representative skin histology (H/E staining). Scale bar = 100 μm. (H) Quantification of epidermal, dermal and total skin thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. (I) TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (J-K) Flow cytometry analysis of the indicated cell types in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (L) RT-qPCR results of Il4 , Il17a and Il33 expression in whole skin. Data are mean + SEM. n = 5 mice per group. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated using 2-tailed unpaired Student t test or Mann-Whitney U test.
    Il 1r Antibody, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il 1r antibody/product/Bio X Cell
    Average 94 stars, based on 1 article reviews
    il 1r antibody - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier
    rabbit anti il 1r  (R&D Systems)
    93
    R&D Systems rabbit anti il 1r
    (A) RT-qPCR results of Ovol1 and Il1a expression in epidermal cells of the HDM/SEB-treated mice at day 7. n = 3 mice per group. (B) Experimental design for <t>IL-1R</t> Ab treatment in (C-K). Samples were harvested at day 11 after treatment for downstream analysis. IgG was used as a control. (C-D) Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (E) Representative photographs of IgG- or IL-1R Ab-treated SSKO mice. (F) Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (G) Representative skin histology (H/E staining). Scale bar = 100 μm. (H) Quantification of epidermal, dermal and total skin thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. (I) TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (J-K) Flow cytometry analysis of the indicated cell types in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (L) RT-qPCR results of Il4 , Il17a and Il33 expression in whole skin. Data are mean + SEM. n = 5 mice per group. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated using 2-tailed unpaired Student t test or Mann-Whitney U test.
    Rabbit Anti Il 1r, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit anti il 1r/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    rabbit anti il 1r - by Bioz Stars, 2026-03
    93/100 stars
    		  Buy from Supplier
    il 1r antibody  (Biorbyt)
    92
    Biorbyt il 1r antibody
    (A) RT-qPCR results of Ovol1 and Il1a expression in epidermal cells of the HDM/SEB-treated mice at day 7. n = 3 mice per group. (B) Experimental design for <t>IL-1R</t> Ab treatment in (C-K). Samples were harvested at day 11 after treatment for downstream analysis. IgG was used as a control. (C-D) Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (E) Representative photographs of IgG- or IL-1R Ab-treated SSKO mice. (F) Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (G) Representative skin histology (H/E staining). Scale bar = 100 μm. (H) Quantification of epidermal, dermal and total skin thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. (I) TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (J-K) Flow cytometry analysis of the indicated cell types in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (L) RT-qPCR results of Il4 , Il17a and Il33 expression in whole skin. Data are mean + SEM. n = 5 mice per group. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated using 2-tailed unpaired Student t test or Mann-Whitney U test.
    Il 1r Antibody, supplied by Biorbyt, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/il 1r antibody/product/Biorbyt
    Average 92 stars, based on 1 article reviews
    il 1r antibody - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for IL-1R Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t

    Journal: Cellular and Molecular Immunology

    Article Title: The AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes epidermal and immune homeostasis in atopic dermatitis-like skin inflammation

    doi: 10.1038/s41423-025-01264-z

    Figure Lengend Snippet: Effects of dermal γδT blockade and IL-1 signaling inhibition on skin inflammation in HDM/SEB-treated SSKO mice. A Experimental design for γδTCR antibody (Ab) treatment. IgG was used as a control. B Representative flow cytometry plots for dermal γδT cells (1) and DETCs (2) among CD45 + CD90.2 + cells. The numbers in the plots represent the relative abundance of the indicated cell populations. C Representative images of IgG- or γδTCR Ab-treated SSKO mice on day 11. D Clinical scores of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. E Representative skin histology (H&E staining) on day 11. Scale bar = 100 μm. F Quantification of epidermal thickness. n = 5 mice per group. G TEWL values of IgG- or γδTCR Ab-treated SSKO mice on day 11. n = 5 mice per group. H Quantification of the number of the indicated cell types per gram of skin tissue in IgG- or γδTCR Ab-treated SSKO mice on day 11. See the legend of Fig. for additional details. n = 5 mice per group. I , J RT‒qPCR results of the indicated genes in the whole skin of HDM/SEB-treated Ctrl (n = 6) and SSKO (n = 5) mice ( I ) or of IgG- or γδTCR Ab-treated SSKO mice (n = 5 mice per group) on day 11 ( J ). K RT‒qPCR results of Ovol1 and Il1a expression in epidermal cells of HDM/SEB-treated mice on day 7. n = 3 mice per group. L Experimental design for IL-1R Ab treatment (M-S). The samples were harvested on day 11 after treatment for downstream analysis. IgG was used as a control. M Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See the legend of Fig. for additional details. n = 4 mice per group. N Representative images of IgG- or IL-1R Ab-treated SSKO mice. O Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. P Representative skin histology (H&E staining). Scale bar = 100 μm. Q Quantification of epidermal thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. R TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. S RT‒qPCR results showing Il4 , Il17a , and Il33 expression in whole skin. n = 5 mice per group. Data are presented as the means ± SEMs. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated via 2-tailed unpaired Student’s t test or the Mann‒Whitney U tes t

    Article Snippet: For IL-1R blocking, the mice were i.p. injected with 200 μg of an anti-IL-1R antibody (BioXcell, Cat# BE0256; Clone JAMA-147) or IgG (BioXcell, Cat# BE0091) at days -1, 0, 3, 7 and 10 of HDM/SEB treatment.

    Techniques: Inhibition, Control, Flow Cytometry, Staining, Expressing

    (A) RT-qPCR results of Ovol1 and Il1a expression in epidermal cells of the HDM/SEB-treated mice at day 7. n = 3 mice per group. (B) Experimental design for IL-1R Ab treatment in (C-K). Samples were harvested at day 11 after treatment for downstream analysis. IgG was used as a control. (C-D) Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (E) Representative photographs of IgG- or IL-1R Ab-treated SSKO mice. (F) Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (G) Representative skin histology (H/E staining). Scale bar = 100 μm. (H) Quantification of epidermal, dermal and total skin thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. (I) TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (J-K) Flow cytometry analysis of the indicated cell types in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (L) RT-qPCR results of Il4 , Il17a and Il33 expression in whole skin. Data are mean + SEM. n = 5 mice per group. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated using 2-tailed unpaired Student t test or Mann-Whitney U test.

    Journal: bioRxiv

    Article Title: An AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes skin homeostasis against atopic dermatitis

    doi: 10.1101/2024.01.29.577821

    Figure Lengend Snippet: (A) RT-qPCR results of Ovol1 and Il1a expression in epidermal cells of the HDM/SEB-treated mice at day 7. n = 3 mice per group. (B) Experimental design for IL-1R Ab treatment in (C-K). Samples were harvested at day 11 after treatment for downstream analysis. IgG was used as a control. (C-D) Flow cytometry analysis of dermal γδT cells in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (E) Representative photographs of IgG- or IL-1R Ab-treated SSKO mice. (F) Clinical scores of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (G) Representative skin histology (H/E staining). Scale bar = 100 μm. (H) Quantification of epidermal, dermal and total skin thickness in IgG- or IL-1R Ab-treated SSKO mice. n = 4 mice per group. (I) TEWL values of IgG- or IL-1R Ab-treated SSKO mice. n = 5 mice per group. (J-K) Flow cytometry analysis of the indicated cell types in the back skin of IgG- or IL-1R Ab-treated SSKO mice. See legends for additional details. n = 4 mice per group. (L) RT-qPCR results of Il4 , Il17a and Il33 expression in whole skin. Data are mean + SEM. n = 5 mice per group. * p < 0.05, ** p < 0.01, *** p < 0.001. p values were calculated using 2-tailed unpaired Student t test or Mann-Whitney U test.

    Article Snippet: For IL-1R blocking, mice were i.p injected with 200 μg IL-1R antibody (BioXcell, Cat# BE0256, Clone JAMA-147) or IgG (BioXcell, Cat# BE0091) at days −1, 0, 3, 7 and 10 of HDM/SEB treatment.

    Techniques: Quantitative RT-PCR, Expressing, Flow Cytometry, Staining, MANN-WHITNEY

    Related to . (A-B) Percentages of different immune cell populations out of total skin cells (A) or skin CD45 + cells (B) in IgG- or IL-1R Ab-treated SSKO mice at day 11. n = 4 mice per group. (C) Clinical scores of skin eruption, scaling, bleeding and redness at day 11. n = 5 mice per group. (D) Quantification of dermal and total skin thickness. n = 4 mice per group. (E) Quantification of the indicated immune cell types per gram of skin tissue at day 11. n = 4 mice per group. (F) RT-qPCR analysis of the indicated genes in whole skin at day 11. n = 5 mice per group. (G) Quantification of the indicated immune cell types per gram of skin tissue in DMSO- or AGX51-treated SSKO mice at day 11. n = 4 mice per group. (H-I) Percentages of different immune cell populations out of total skin cells (H) or skin CD45 + cells (I) at day 11. n = 4-5 mice per group. (J) RT-qPCR results of the indicated genes in the whole skin at day 11. Data are mean + SEM. n = 4 mice per group. * p < 0.05, ** p < 0.01. p values were calculated using 2-tailed unpaired Student t test.

    Journal: bioRxiv

    Article Title: An AhR-Ovol1-Id1 regulatory axis in keratinocytes promotes skin homeostasis against atopic dermatitis

    doi: 10.1101/2024.01.29.577821

    Figure Lengend Snippet: Related to . (A-B) Percentages of different immune cell populations out of total skin cells (A) or skin CD45 + cells (B) in IgG- or IL-1R Ab-treated SSKO mice at day 11. n = 4 mice per group. (C) Clinical scores of skin eruption, scaling, bleeding and redness at day 11. n = 5 mice per group. (D) Quantification of dermal and total skin thickness. n = 4 mice per group. (E) Quantification of the indicated immune cell types per gram of skin tissue at day 11. n = 4 mice per group. (F) RT-qPCR analysis of the indicated genes in whole skin at day 11. n = 5 mice per group. (G) Quantification of the indicated immune cell types per gram of skin tissue in DMSO- or AGX51-treated SSKO mice at day 11. n = 4 mice per group. (H-I) Percentages of different immune cell populations out of total skin cells (H) or skin CD45 + cells (I) at day 11. n = 4-5 mice per group. (J) RT-qPCR results of the indicated genes in the whole skin at day 11. Data are mean + SEM. n = 4 mice per group. * p < 0.05, ** p < 0.01. p values were calculated using 2-tailed unpaired Student t test.

    Article Snippet: For IL-1R blocking, mice were i.p injected with 200 μg IL-1R antibody (BioXcell, Cat# BE0256, Clone JAMA-147) or IgG (BioXcell, Cat# BE0091) at days −1, 0, 3, 7 and 10 of HDM/SEB treatment.

    Techniques: Quantitative RT-PCR